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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XDH
All Species:
13.33
Human Site:
T222
Identified Species:
29.33
UniProt:
P47989
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47989
NP_000370.2
1333
146424
T222
E
L
L
R
L
K
D
T
P
R
K
Q
L
R
F
Chimpanzee
Pan troglodytes
XP_525729
1333
146376
T222
E
L
L
R
L
K
D
T
P
R
K
Q
L
R
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540143
1333
147201
V223
E
L
L
R
L
K
D
V
P
Q
K
Q
L
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q00519
1335
146500
T224
E
L
L
R
L
K
D
T
P
R
K
T
L
R
F
Rat
Rattus norvegicus
P22985
1331
146224
T221
E
L
L
R
L
K
D
T
P
Q
K
K
L
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509432
1297
142673
A222
E
L
L
L
L
K
D
A
P
R
R
Q
L
R
F
Chicken
Gallus gallus
P47990
1358
149595
K248
E
L
M
T
Q
R
N
K
E
Q
K
Q
V
C
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688983
1351
148155
Q239
E
L
V
S
L
S
K
Q
T
Q
R
E
M
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10351
1335
146909
F220
E
L
Q
L
S
D
A
F
D
S
Q
S
L
I
F
Honey Bee
Apis mellifera
XP_001119950
1356
152206
L254
K
L
H
I
S
S
Y
L
D
E
E
Y
L
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G192
1321
144562
C223
D
S
G
M
Y
R
W
C
S
P
A
S
V
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.4
N.A.
89.1
90.3
N.A.
70.4
72.3
N.A.
67.8
N.A.
52.6
52.4
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.4
N.A.
95.1
95.8
N.A.
82.3
84
N.A.
81.4
N.A.
69.5
70.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
93.3
86.6
N.A.
80
33.3
N.A.
33.3
N.A.
26.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
93.3
100
N.A.
86.6
66.6
N.A.
66.6
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
19
0
% C
% Asp:
10
0
0
0
0
10
55
0
19
0
0
0
0
0
0
% D
% Glu:
82
0
0
0
0
0
0
0
10
10
10
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
82
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
10
% I
% Lys:
10
0
0
0
0
55
10
10
0
0
55
10
0
0
0
% K
% Leu:
0
91
55
19
64
0
0
10
0
0
0
0
73
0
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
55
10
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
0
0
10
0
37
10
46
0
0
0
% Q
% Arg:
0
0
0
46
0
19
0
0
0
37
19
0
0
55
0
% R
% Ser:
0
10
0
10
19
19
0
0
10
10
0
19
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
37
10
0
0
10
0
0
0
% T
% Val:
0
0
10
0
0
0
0
10
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _